Availability
- Request Lead Time
- In stock and ready for quick dispatch
- Usually dispatched within 5-10 working days
Product Overview
Product Name | Adiponectin Polyclonal Antibody |
---|---|
Catalog Number | GRP246 |
Species/Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Conjugation | Unconjugated |
Tested applications | IHC-P, WB |
Immunogen | KLH conjugated synthetic peptide derived from human Adiponectin (public_immunogen_range: 140-190/244) |
Alternative Names | (click to expand) |
Product Properties
Product Description
Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.
Application Notes
Dilution Range | WB: 1:300-1000, IHC-P: 1:200-400 |
---|
Reviews
Write Your Own Review